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Primary Animal Models for Combination Therapy: The HALT Program

Dennis Carson, M.D., Moores Cancer Center

April 21, 2011
12 minutes
Dennis Carson


Dennis Carson, M.D. is Director of the Rebecca and John Moores UCSD Cancer Center and Professor of Medicine at UCSD School of Medicine. He is also Associate Dean for Cancer Affairs and holder of the Chugai Pharmaceutical Chair in Cancer. Dr. Carson is perhaps best known for his landmark work in developing the agent 2-chlorodeoxyadenosine, or 2-CdA, for the treatment of hairy cell leukemia. This drug, now marketed as Leustatin, is the treatment of choice for this disease and has resulted in long term, complete remissions in about 75 percent of patients, often after just a single infusion. It is also effective in other lymphoid cancers, multiple sclerosis and psoriasis.