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Stem Cell Research in Diabetes and Metabolism

Harvard Stem Cell Institute Panel


This panel was made up of  Kenneth Zaret, Douglas Melton, E. Edward Baetge, Jacob Hanna,
Armand Keating and Jonathan Graff, and moderated by Amy Wagers and Gordon Weir.

Kenneth Zaret is the Joseph Leidy Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine. His research focuses on understanding gene activation and cell specification in embryonic development. Other research interests include mammalian gene regulation, cell differentiation and chromatin structure.

Doug Melton is the Thomas Dudley Cabot Professor in the Department of Natural Sciences at Harvard University and an Investigator of the Howard Hughes Medical Institute. He is also Co-director of Harvard’s Stem Cell Institute. Dr. Melton’s research focuses on the developmental biology of the pancreas.

E. Edward Baetge is the Senior Vice President and Chief Scientific Officer of Novocell. Baetge held management positions at CytoTherapeutics from 1992-1997 and at Bristol-Myers Squibb from 1987-1992 . He holds a Ph.D. in molecular neurobiology from Cornell University and completed postdoctoral work at Cornell University and the Howard Hughes Medical Institute. Dr. Baetge has published extensively in the field of cell therapy and has produced a number of cell technology patents.

Jacob Hanna is a postdoctoral fellow in Whitehead Member Rudolf Jaenisch’s lab. His research is focused on innovative cell reprogramming to form embryonic stem cell like pluripotent cells.

Armand Keating is the Director of the Division of Hematology and Professor of Medicine at the University of Toronto. He is also a Senior Scientist in the Division of Experimental Terapeutics at Toronto General Research Institute. He is a Member and Clinical Research Unit Executive at the Ontario Cancer Institute. Dr. Keating’s research focuses on marrow mesenchymal stromal cells (MSCs) and hematopoietic progenitor cells in tissue regeneration.

Jonathan Graff is Associate professor in the Department of Developmental and Molecular Biology at the Graduate School of Biomedical Sciences. His research focuses on adipose tissue formation and function, homeostasis, and mechanisms regarding nutrient and energy regulation. 

Amy Wagers is Principal Investigator in the section on Developmental and Stem Cell Biology at Joslin Diabetes Center and Assistant Professor in the Department of Pathology at Harvard Medical School. Dr. Wagers is a recipient of the Burroughs Wellcome Fund Career Award in the Biomedical Science and the Smith Family New Investigator Award. Her current research is focused on defining the factors and mechanisms that regulate the migration, expansion, and regenerative potential of adult hematopoietic and adult skeletal muscle precursor stem cells.

Gordon Weir is Professor of Medicine at Harvard Medical School, Diabetes Research and Wellness Foundation Chair, and heads Joslin’s Section on Islet Transplantation and Cell Biology. He served as the Joslin Center’s Medical Director for nine years and served on the editorial boards of the American Journal of Physiology and Journal of Clinical Endocrinology and Metabolism, and Transplantation.