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Keynote: Accelerating Drug Development and Biomarker Discovery: The I-SPY Trials

Laura Esserman, M.D., M.B.A., Carol Franc Buck Breast Care Center, UCSF Helen Diller Family Comprehensive Cancer Center

April 21, 2011
42 minutes
Laura Esserman


Dr. Laura Esserman, MD, MBA, is a Professor of Surgery and Radiology at UCSF and is the Director of the Carol Franc Buck Breast Care Center, an interdisciplinary clinical program where clinical research and quality improvement is integral to care. She is the clinical leader of the Breast Oncology Program of the NCI designate Comprehensive Cancer Center. She is founder and faculty leader of the program in Translational Informatics spanning the disciplines of bioinformatics, medical and clinical informatics, systems integration, and clinical care delivery. In 1996, she started the Center of Excellence for Breast Cancer Care to integrate clinical care and research, automate tools for the capture of patient and clinical data, and develop systems to tailor care to biology, patient preference, and performance. Dr. Esserman is nationally and internationally known as a leader in breast cancer and has published over 150 articles. She is the Principle Investigator of the I-SPY Trial program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design. Dr. Esserman is currently developing a University of California-wide breast cancer initiative designed to follow 400,000 women from screening through treatment and outcomes incorporating the latest in molecular testing and web-based tools into the course of care called the ATHENA Project.