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• CCB Symposium 2011 - From Cells to Clinic

UCSD's newly formed Center for Chronobiology (CCB) hosted its 2nd annual chronobiology symposium on February 9-11, 2011. The theme for the symposium was "From Cells to Clinic." A select, stellar group of chronobiologists attended and spoke at the conference. The aims of the conference were to: 1. Provide participants with a comprehensive view of modern Chronobiology. 2. Exchange a broad spectrum of ideas and techniques in Chronobiology. 3. Promote interactions among the faculty and lab personnel of the UCSD Center for Chronobiology, the invited speakers, and other participants. 4. Further acquaint the speakers, their groups, and other registrants with the depth and breadth of Chronobiology research conducted at UCSD. Chronobiology is the biology of time, or the study of internal biological clocks. Biological clocks are found at all levels in living organisms. They range from oscillations found in nerve cells on the millisecond scale to oscillations in minutes, hours, days, and years in a variety of organisms and tissues. Although the commonly used phrase "your biological clock is ticking" relates to the window of years for becoming parents, many clocks are found in humans, such as the time to puberty, to menopause, and aging "clocks." Our research unit is focused on just one of these chronobiological phenomena: the daily or circadian clock. The name circadian comes from the Latin circa, meaning "approximately," and diem or dies, "day;" thus, the word means "about one day." Examples of human health issues related to circadian rhythms—biological oscillations in activity that recur with a period of “about one day”—are the problems associated with jet lag and shift work, the depression of Seasonal Affective Disorder, and time-of-day differences in response to medications and treatments.

• Videos

• CCB Symposium 2011 Panel CCB Symposium: From Cells to Clinic, UCSD, CA February 2011 February 10, 2011 Speakers: Susan Golden, Andrew Millar, Deborah Bell-Pedersen, John O'Neill Run Time: 56 minutes Chronobiologists Susan Golden, Andrew Millar, Deborah Bell-Pedersen, John O'Neill discuss a broad spectrum of ideas and techniques in Chronobiology...

• The Science Studio with Andrew Millar University of Edinburgh February 10, 2011 Speakers: Andrew Millar Run Time: 26 minutes Andrew Millar holds a Chair of Systems Biology at the University of Edinburgh, where he directs the Centre for Systems Biology at Edinburgh...

• How bacteria tell time Susan Golden, University of California, San Diego February 9, 2011 Speakers: Susan Golden Susan Golden is a Distinguished Professor in the Section of Molecular Biology, and Director of the Center for Chronobiology at the University of...

• The costs and advantages of complexity in biological networks Andrew Millar, University of Edinburgh February 9, 2011 Speakers: Andrew Millar Run Time: 35 minutes Andrew Millar holds a Chair of Systems Biology at the University of Edinburgh, where he directs the Centre for Systems Biology at Edinburgh...

• The inside story on human sleep spindles Terry Sejnowski, Salk Institute for Biological Studies and UCSD February 11, 2011 Speakers: Terry Sejnowski Run Time: 43 minutes Terrence J. Sejnowski is an HHMI investigator, the Francis Crick Professor and Director of the Crick-Jacobs Center for Theoretical and Computational...

• An introduction by Stuart Brody Professor Emeritus in the Section of Molecular Biology at the University of California, San Diego February 9, 2011 Speakers: Stuart Brody Run Time: 05 minutes

• Ionic mechanisms underlying circadian oscillations Chris Colwell, UCLA February 10, 2011 Speakers: Chris Colwell Run Time: 48 minutes Christopher Colwell is a Professor at the UCLA School of Medicine

• Non-transcriptional mechanisms are sufficient to sustain circadian rhythms in eukaryotes John O'Neill, University of Cambridge February 10, 2011 Speakers: John O'Neill Run Time: 43 minutes John O’Neill is a Research Fellow at the Institute of Metabolic Science, Metabolic Research Laboratories, at the University of Cambridge.

• Post-translation mechanisms in the plant circadian clock David Somers, Ohio State University February 10, 2011 Speakers: David Somers Run Time: 29 minutes David Somers is an Associate Professor in the Department of Plant Cellular and Molecular Biology at The Ohio State University

• State dependence of the intracellular calcium signals generated in SCN neurons by excitatory neurotransmission Charles Allen, Oregon Health & Science University February 11, 2011 Speakers: Charles Allen Run Time: 34 minutes Charles Allen is a Senior Scientist in the Center for Research on Occupational and Environmental Toxicology at Oregon Health & Science University...

• What do ganglion-cell photoreceptors tell the clock? David Berson, Brown University February 11, 2011 Speakers: David Berson Run Time: 42 minutes David Berson is a Professor in the Department of Neuroscience at Brown University.